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Aug 12, 2023

Turning cooperative bacteria into probiotics for human health

Yolanda Sanz is in the Microbiome, Nutrition & Health Research Unit, Institute of Agrochemistry and Food Technology, Severo Ochoa Centre of Excellence, National Research Council (IATA-CSIC), 46980 Paterna-Valencia, Spain.

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The microbial communities in the human gut function as a bioreactor that breaks down nutrients (mainly complex indigestible carbohydrates) and liberates bioactive substances to drive microbe–host interactions and shape host health and disease. Bacteria inhabiting the gut also interact to increase their ability to survive as a team. Disentangling this complex, symbiotic relationship should provide opportunities to promote health. Writing in Nature, Khan et al.1 report efforts to harness a beneficial partnership between species of gut bacteria.

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doi: https://doi.org/10.1038/d41586-023-02407-w

Khan, M. T. et al. Nature https://doi.org/10.1038/s41586-023-06378-w (2023).

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Romaní-Pérez, M., Agusti, A. & Sanz, Y. Curr. Opin. Clin. Nutr. Metab. Care 20, 484–491 (2017).

Article PubMed Google Scholar

Oliveira, R. A. & Palmer, E. G. Cell Host Microbe 31, 472–484 (2023).

Article PubMed Google Scholar

Sokol, H. et al. Proc. Natl Acad. Sci. USA 105, 16731–16736 (2008).

Article PubMed Google Scholar

Feng, J. et al. Cell Host Microbe 30, 200–215 (2022).

Article PubMed Google Scholar

Hodgkinson, K. et al. Clin. Nutr. 42, 61–75 (2023).

Article PubMed Google Scholar

Li, Z. et al. Gut 67, 1269–1279 (2018).

Article PubMed Google Scholar

Sarkar, A. et al. Cell Death Dis. 14, 332 (2023).

Article PubMed Google Scholar

Gómez Del Pulgar, E. M., Benítez-Páez, A. & Sanz, Y. Nutrients 12, 551 (2020).

Article PubMed Google Scholar

Paquet, J.-C. et al. Front. Med. (Lausanne) 8, 716266 (2021).

Article PubMed Google Scholar

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The author declares no competing interests.

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