Turning cooperative bacteria into probiotics for human health
Yolanda Sanz is in the Microbiome, Nutrition & Health Research Unit, Institute of Agrochemistry and Food Technology, Severo Ochoa Centre of Excellence, National Research Council (IATA-CSIC), 46980 Paterna-Valencia, Spain.
You can also search for this author in PubMed Google Scholar
The microbial communities in the human gut function as a bioreactor that breaks down nutrients (mainly complex indigestible carbohydrates) and liberates bioactive substances to drive microbe–host interactions and shape host health and disease. Bacteria inhabiting the gut also interact to increase their ability to survive as a team. Disentangling this complex, symbiotic relationship should provide opportunities to promote health. Writing in Nature, Khan et al.1 report efforts to harness a beneficial partnership between species of gut bacteria.
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
doi: https://doi.org/10.1038/d41586-023-02407-w
Khan, M. T. et al. Nature https://doi.org/10.1038/s41586-023-06378-w (2023).
Article Google Scholar
Romaní-Pérez, M., Agusti, A. & Sanz, Y. Curr. Opin. Clin. Nutr. Metab. Care 20, 484–491 (2017).
Article PubMed Google Scholar
Oliveira, R. A. & Palmer, E. G. Cell Host Microbe 31, 472–484 (2023).
Article PubMed Google Scholar
Sokol, H. et al. Proc. Natl Acad. Sci. USA 105, 16731–16736 (2008).
Article PubMed Google Scholar
Feng, J. et al. Cell Host Microbe 30, 200–215 (2022).
Article PubMed Google Scholar
Hodgkinson, K. et al. Clin. Nutr. 42, 61–75 (2023).
Article PubMed Google Scholar
Li, Z. et al. Gut 67, 1269–1279 (2018).
Article PubMed Google Scholar
Sarkar, A. et al. Cell Death Dis. 14, 332 (2023).
Article PubMed Google Scholar
Gómez Del Pulgar, E. M., Benítez-Páez, A. & Sanz, Y. Nutrients 12, 551 (2020).
Article PubMed Google Scholar
Paquet, J.-C. et al. Front. Med. (Lausanne) 8, 716266 (2021).
Article PubMed Google Scholar
Download references
Reprints and Permissions
The author declares no competing interests.
Read the paper: Synergy and oxygen adaptation for development of next-generation probiotics
Gut microbes shape athletic motivation
Probiotic prevents infections in newborns
See all News & Views
Revisiting the intrinsic mycobiome in pancreatic cancer
Matters Arising 02 AUG 23
Synergy and oxygen adaptation for development of next-generation probiotics
Article 02 AUG 23
NIH launches trials for long-COVID treatments: what scientists think
News 01 AUG 23
Alzheimer’s drug trials plagued by lack of racial diversity
News 02 AUG 23
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer
Article 02 AUG 23
Consent document translation expense hinders inclusive clinical trial enrolment
Article 02 AUG 23
The professorship is associated with the management of a department in the field of vegetative physiology.
Tübingen, Baden-Württemberg (DE)
University of Tübingen – Faculty of Medicine
Founded in 1897, Zhejiang University (ZJU) ranks among the top 3 universities on Chinese mainland and within the top 100 in the Times Higher Educat...
Hangzhou, Zhejiang (CN)
Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine(ZJUSS)
The Chan Lab in the Human Oncogenesis & Pathogenesis Program at Memorial Sloan Kettering Cancer Center is seeking a highly motivated and successful...
New York City, New York (US)
Havas People LLC
An der Medizinischen Fakultät der Rheinischen Friedrich-Wilhelms-Universität Bonn a W2-Professur für Herzelektrophysiologie soll schnellstmöglich am
Bonn, Nordrhein-Westfalen (DE)
Rheinische Friedrich-Wilhelms-Universität
Join a world-class photovoltaics research group Contribute to the development of the next generation of solar cells Opportunities for industry ...
Canberra, Australian Capital Territory (AU)
The Australian National University- School of Engineering